PITT-CMCR Program Objectives

The University of Pittsburgh Center for Countermeasures Against Radiation CMCR Program is seeking applications from new and established basic scientists seeking radiation biology and radiation chemistry training for the purpose of developing data suitable for application for an independent research grant (K-Award, R21, RO1). The program is also focused on recruiting chemists into the field of radiation biology. Therefore, ideal candidates are recent Ph.D. students initiating or seeking a postdoctoral fellowship in the fields of radiation chemistry or radiation biology. The overall Pitt-CMCR Program is focused on discovery of new radiation mitigators (delivered after radiation) for in vitro and in vivo testing leading to FDA approval and addition to the national stockpile for treating large numbers of exposed military or civilian populations exposed to ionizing irradiation and to use in conditions of radiation accidents or willful acts of radiation terrorism. Therefore, the program is focused on the fields of radiation biology and radiation chemistry.

The Program

Four basic project laboratories (beginning September 1, 2015, year 11) are associated with the CMCR grant. Laboratories include:

  1. Joel S. Greenberger, M.D.
  2. Valerian Kagan, Ph.D.
  3. Hulya Bayir, M.D.
  4. Jian Yu, Ph.D.

Pilot project recipients will be working with these laboratories and the core facilities of the Pitt-CMCR. These core facilities include: Support for the use of animal models for radiation mitigators: Innovative Medicinal Chemistry (Peter Wipf, Ph.D., Detcho Stoyanovsky, Ph.D.), Biostatistics (Hong Wang, Ph.D.), Radiobiological Standardization (Michael W. Epperly, Ph.D.), Computational Systems Pharmacology (Ivet Bahar, Ph.D.), Lipidomics and Bioanalytical (Yulia Tyurina, Ph.D.), and Imaging Radiation Pathology (Simon Watkins, Ph.D.).